{"id":632858,"date":"2025-09-28T06:22:20","date_gmt":"2025-09-28T05:22:20","guid":{"rendered":"https:\/\/theplayoffs.news\/en\/?p=632858"},"modified":"2025-09-28T06:23:37","modified_gmt":"2025-09-28T05:23:37","slug":"nfl-week-4-49ers-vs-jaguars-injury-report-major-updates-on-brock-purdy-jauan-jennings-and-ricky-pearsall","status":"publish","type":"post","link":"https:\/\/theplayoffs.news\/en\/nfl-week-4-49ers-vs-jaguars-injury-report-major-updates-on-brock-purdy-jauan-jennings-and-ricky-pearsall\/","title":{"rendered":"NFL Week 4 \u2013 49ers vs. Jaguars Injury Report: Major Updates on Brock Purdy, Jauan Jennings, and Ricky Pearsall as San Francisco Faces Key Depth Questions"},"content":{"rendered":"<p>The San Francisco 49ers enter Week 4 unbeaten at 3-0, leaning on a defense that has kept opponents in check and an offense that&rsquo;s been efficient through the air. They&rsquo;ve been moving the ball well, ranking near the top of the league in passing yards, but haven&rsquo;t always turned that production into points.<\/p><p>Christian McCaffrey continues to be the centerpiece, while young receivers are stepping up to give San Francisco balance. At home, they&rsquo;ll look to dictate tempo early and avoid the slow starts that have kept games closer than expected.<\/p><figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\"><p lang=\"en\" dir=\"ltr\">Christian McCaffrey is the 1st player with 50+ carries and 25+ catches through the 1st 3 weeks of a season since Thurman Thomas in 1991. <a href=\"https:\/\/t.co\/qc8eWWtwH5\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>pic.twitter.com\/qc8eWWtwH5<\/a><\/p>&mdash; NFL Stats (@NFL_Stats) <a href=\"https:\/\/twitter.com\/NFL_Stats\/status\/1970620455930187968?ref_src=twsrc%5Etfw\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>September 23, 2025<\/a><\/blockquote><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div><\/figure><p><a href=\"https:\/\/theplayoffs.news\/en\/tag\/jacksonville-jaguars\/\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"trk-cta-link\" data-cta-trk='{\"ctaType\":\"Link\",\"ctaSubType\":\"main\"}'>Jacksonville Jaguars<\/a>, at 2-1, has built its success on a defense that thrives on takeaways and a ground game that controls possession. Travis Etienne has been the steady force, while Trevor Lawrence has shown flashes but still needs to cut down on turnovers.<\/p><p>The Jaguars&rsquo; ability to win the turnover battle has been their edge, and they&rsquo;ll need it again against a 49ers team that can pile up yards quickly. History favors San Francisco in this matchup, but Jacksonville&rsquo;s defensive opportunism and strong run game suggest this could be a tighter contest than past meetings.<\/p><h2 style=\"margin-bottom:15px\">Jacksonville Jaguars Injury Report for Game Against San Francisco 49ers<\/h2><div style=\"margin-bottom:30px\">\n<table style=\"border-collapse: collapse;width: 100%;font-family: 'Times New Roman', Times, serif;font-size: 12pt\">\n  <thead>\n    <tr style=\"background-color: #f2f2f2;border: 1px solid #000\">\n      <th style=\"padding: 8px;border: 1px solid #000\">PLAYER NAME<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">POS<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">STATUS<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">UPDATE<\/th>\n    <\/tr>\n  <\/thead>\n  <tbody>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Yasir Abdullah<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">LB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Abdullah (hamstring) has been downgraded and ruled out ahead of Sunday&rsquo;s matchup against the 49ers.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Wyatt Milum<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">G<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Milum (knee) has been ruled out for Sunday&rsquo;s contest against the 49ers.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Dyami Brown<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Brown (shoulder) is listed as questionable for Sunday&rsquo;s game against the 49ers after practicing in a limited fashion Thursday and Friday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Jalen McLeod<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">LB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">McLeod (lower body) was placed on injured reserve with a designation to return Tuesday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Caleb Ransaw<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">CB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jacksonville placed Ransaw (lower body) on its injured reserve list Tuesday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Joshua Cephus<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Cephus (undisclosed) reverted to injured reserve with the Jaguars on Thursday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Cooper Hodges<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">OT<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Hodges (knee) cleared waivers and reverted to Jacksonville&rsquo;s PUP list Thursday.<\/td>\n    <\/tr>\n  <\/tbody>\n<\/table>\n<\/div><h2 style=\"margin-bottom:15px\">San Francisco 49ers Injury Report for Game Against Jacksonville Jaguars<\/h2><div style=\"margin-bottom:30px\">\n<table style=\"border-collapse: collapse;width: 100%;font-family: 'Times New Roman', Times, serif;font-size: 12pt\">\n  <thead>\n    <tr style=\"background-color: #f2f2f2;border: 1px solid #000\">\n      <th style=\"padding: 8px;border: 1px solid #000\">PLAYER NAME<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">POS<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">STATUS<\/th>\n      <th style=\"padding: 8px;border: 1px solid #000\">UPDATE<\/th>\n    <\/tr>\n  <\/thead>\n  <tbody>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jauan Jennings<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jennings (ankle\/shoulder) is expected to suit up for Sunday&rsquo;s game versus the Jaguars.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Ricky Pearsall<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Pearsall (knee) is slated to play Sunday versus the Jaguars.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">CJ West<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">DT<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">West (thumb) has been ruled out for Sunday&rsquo;s contest against Jacksonville.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Renardo Green<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">CB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Green (neck) is questionable to play Sunday against the Jaguars.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jordan Watkins<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Watkins (calf) has been ruled out for Sunday&rsquo;s contest against the Jaguars\n    <\/td><\/tr><tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Nick Bosa<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">DE<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Bosa (knee) underwent surgery to address his torn ACL on Friday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Mac Jones<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">QB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jones (knee) is listed as questionable for Sunday&rsquo;s contest versus the Jaguars.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Brandon Aiyuk<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Aiyuk (knee, PUP) is not close to returning.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Connor Colby<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">G<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Questionable<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Colby is listed as questionable.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Spencer Burford<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">OT<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Burford (knee) was placed on injured reserve Saturday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Ben Bartch<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">G<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Bartch (ankle) was placed on injured reserve Wednesday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">George Kittle<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">TE<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">The 49ers placed Kittle (hamstring) on injured reserve Tuesday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jakob Robinson<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">CB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Robinson (forearm) was placed on injured reserve Tuesday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Jacob Cowing<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">The 49ers placed Cowing (hamstring) on injured reserve Wednesday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Kevin Givens<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">DT<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Givens (pectoral) was placed on injured reserve Tuesday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Malik Mustapha<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">S<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Mustapha (knee) was placed on the reserve\/PUP list Tuesday.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Kurtis Rourke<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">QB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Out<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Rourke (knee) was placed on the reserve\/non-football injury list Tuesday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Patrick Taylor Jr.<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">RB<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Taylor will undergo season-ending surgery to repair a fracture in his shoulder.<\/td>\n    <\/tr>\n    <tr>\n      <td style=\"padding: 8px;border: 1px solid #000\">Tarron Jackson<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">DE<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Jackson (undisclosed) was discharged from the hospital and returned to the 49ers&rsquo; training camp Monday.<\/td>\n    <\/tr>\n    <tr style=\"background-color: #f9f9f9\">\n      <td style=\"padding: 8px;border: 1px solid #000\">Trent Taylor<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">WR<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">Injured Reserve<\/td>\n      <td style=\"padding: 8px;border: 1px solid #000\">The 49ers placed Taylor (undisclosed) on injured reserve Tuesday.<\/td>\n    <\/tr>\n    <tr>\n<\/tr><\/tbody><\/table><\/div>\n<div class=\"mm-layout mm-layout-type-post mm-layout-slot4\">\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The San Francisco 49ers enter Week 4 unbeaten at 3-0, leaning on a defense that has kept opponents in check and an offense that&rsquo;s been efficient through the air. They&rsquo;ve been moving the ball well, ranking near the top of the league in passing yards, but haven&rsquo;t always turned that production into points. Christian McCaffrey [&hellip;]<\/p>\n","protected":false},"author":39,"featured_media":632843,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_mux_skip_reasons":[],"footnotes":""},"categories":[3],"tags":[166,264],"class_list":["post-632858","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nfl","tag-jacksonville-jaguars","tag-san-francisco-49ers"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NFL Week 4 &ndash; 49ers vs. Jaguars Injury Report: Major Updates on Brock Purdy, Jauan Jennings, and Ricky Pearsall as San Francisco Faces Key Depth Questions - The Playoffs<\/title>\n<meta name=\"description\" content=\"Get the full 49ers vs. Jaguars Week 4 injury report with major updates on Brock Purdy, Jauan Jennings, and Ricky Pearsall.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/theplayoffs.news\/en\/nfl-week-4-49ers-vs-jaguars-injury-report-major-updates-on-brock-purdy-jauan-jennings-and-ricky-pearsall\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NFL Week 4 &ndash; 49ers vs. Jaguars Injury Report: Major Updates on Brock Purdy, Jauan Jennings, and Ricky Pearsall as San Francisco Faces Key Depth Questions - 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